A: No, it’s not safe to take. Find out what else works on blood sugar level… like diet, weight management, and exercise. Read about Avandia here:
Read about diet, weight management, and exercise here:
I take Metformin. That, combined with good diet and exercise, works very well for many folks.
Q: What is the difference between Actos and Avandia. Does Actos have the same side effects as Avandia?
Lately Avandia has been associated with heart failure according to New England Medical Journal. Actos is also being associated with this risk being a similar salt to Avandia. Does anyone know the similarities and differences between the two drugs
A: I disagree with the above poster. I think this is a battle for market share.
The New England Journal of Medicine was really taken to task for publishing the Avandia article. Read the article for yourself. Also read the scathing response in the Lancet, an equally well-respected British medical journal.
Then talk to your doctor about how this (old) data applies to your particular situation. As with all meds, you must ask whether the benefits outweigh the risks. Often they really do.
What bugs me about this one is the way it was driven, funded, published and hyped.
Q: What do you think of this statement about Avandia?
CBS News – 43 minutes ago
(WebMD) There’s no urgent need for type 2 diabetes patients to stop taking Avandia, even if the drug really does increase the risk of heart attack, some medical experts caution.
A: I have already answered a question about rosiglitazone/Avandia. Rosiglitazone belongs to a family of drugs which reduce the body’s resistance to the effects of insulin. This is a very important class of drugs for type 2 diabetics for whom insulin resistance is universally present leading to increasing production of insulin and eventually pancreatic beta cell failure and the inability to produce insulin. The first drug in this class used in the United States was troglitazone. It was withdrawn by the company for fear of lawsuits. The problem was not with the drug itself it was that physicians ignored warnings that the drug was not for everyone. The 2 remaining drugs in this class in the US are rosiglitazone and pioglitazone/Actos. It is frequently stated in the medical literature that pioglitazone increases the risk of heart failure although there is absolutely no evidence to support this claim. The study which alleges that rosiglitazone may lead to cardiovascular events such as heart attacks, strokes, and deaths has serious flaws which I will outline below. This study is of more interest to attorneys who smell money than it is to physicians. As such the Food and Drug Administration at this time has stated that they have no intention of placing warnings or restrictions on rosiglitazone. The study you are referring to was a meta-analysis. Meta-analysis are by their very definition statistically ‘invalid’. They are intended to identify areas where additional study is needed – meta-analysis is never intended to generate ‘hard’ data, conclusions, or to become the basis for changes in medical practice. A meta-analysis sums up the results of a variety of studies. Such studies have different designs and are designed to answer different questions. It should be obvious that a summation of such data would have inherent limitations. That being said the meta-analysis was a summation of studies of short duration and studies of short duration introduce significant bias for a variety of reasons. The full effect of drugs – for benefit or harm – may take months or years and the likelihood of events is quite different in the short run as opposed to the long run. Finally – the number of events were few – too few in my opinion to lead to any conclusion. For example – 18 people on rosiglitazone as opposed to 12 people on other treatment suffered adverse events. It is true that this is a 50% increase but something which is statistically significant may not be clinically relevant. For example – a study of a drug to increase exercise tolerance in people with narrowing of the arteries in the legs found that the drug produced a statistically significant increase in exercise tolerance. In fact – however – people were able to walk only 3 additional steps. This illustrates the difference between statistics which are easily manipulated and clinically relevant data. Personally I have always preferred pioglitazone to rosiglitazone but not because I believe that the former is safer. No one on rosiglitazone should stop the drug without consulting their physician. Again – at this point this is a legal concern rather than a medical concern. Many drugs are withdrawn after such articles as companies fear lawsuits. Physicians must practice in accordance with the medical literature and not out of fear of attorneys.
Q: What are good alternatives to Avandia for treating type II Diabetes?
I”ve been on Avandia for 3 years, and take metformin as well. Now today, news stories show significantly increased heart attack risk with Avandia, and since heart disease runs in my family, I’d rather not chance it. Plus, Avandia makes it really hard to keep weight down, in my experience.
A: It is very likely going to be a class effect, so Actos is not an appropriate alternative.
The Avandia story has been over-hyped. Read the response in the Lancet, another respected journal.
All diabetics are at risk for heart disease regardless of which medication they use.
Talk it over with your doctor.
Q: Are there any recalls on avandia or adavent made by park davis?
MY MOTHER IS NOW 78. SHE WAS PRESCRIBED AVANDIA AND ADAVENT. It caused her a stroke and park davis is the maker and the drug and food administration never answered the complaint.
A: You can contact them again if they dont bothet to answer you can file suit against them.
Avandia has also been linked to more dangerous side effects such as:
* Heart problems
* Heart failure
Individuals who are taking Avandia and experience fluid retention or swelling, shortness of breath, unusual tiredness or increase in weight should consult with a physician immediately.
In 2000, Rezulin diabetes drug was recalled after being linked to dozens of fatal liver disease instances. The FDA announced at the time of the Rezulin recall that Actos and Avandia were safer alternatives for managing Type 2 diabetes. At the time, the consumer group Public Citizen criticized the FDA for waiting too long to issue the Rezulin recall and remained skeptical that other drugs, such as Avandia, would not also cause problems.
Since that time, several studies have been published linking Avandia to congestive heart failure and other heart problems. Unfortunately, millions of Americans have already taken Avandia, and one expert estimates that thousands have suffered heart problems as a result.
Contact an Avandia Attorney
If you suffered congestive heart failure or other Avandia side effect while taking this drug, it is advisable to consult with attorney experienced in dangerous drug litigation as soon as possible. You may be able to hold the drug company responsible for your damages. Contact us today to learn more.(http://www.adrugrecall.com/avandia/contact.html)
Q: Is there an aternitive medicine for Avandia?
I have no insurance and the price of avandia is keeping me from buying it. Is there anything that I can replace it with. Thanks for the help.
A: Talk to an herbalist in your area about cinnamon. Cinnamon is showing great promise for some people. Will it get you off Avandia? Who knows, but it could be worth a shot.
Q: Can someone tell me a website for I WILL It is a test for people taking Avandia with bad blood sugars?
This I WILL was on TV. There was a 866 number I think. It is for people that cant control their blood sugars taking Avandia and another Medication. You can get free testing if you qualify. Please help me find this phone number. I think it is 866 something something I WILL. HELP ME PLEASE. TYVM!
A: My dear friend i searched all over the internet and could not find what you are asking for,,,, sorry,, if you type diabetes into your browser there are many links that can be informative and also an alternative to heavy medication,,
I wish you the best and please keep it under control,, I had an uncle who lost a leg over this,
Q: I stop taking avandia 4mg because of the warning, I did not tell doctor. How much points does avandia drop?
I stop taking avandia 4mg because of the warning, I did not tell doctor. How much points does avandia drop the sugar down anyways.
I do the 4 mg tablet.
I need help with this.
A: Of course you need help with this.
Never discontinue any medication because of a news bite.No one person gets the same effect from any medication.Avandia may lower your sugar by so many points and mine a different amount.Each of us is different.
Call your doctor and wok out a better med schedule for you.
Q: Why do the politicians beat up on Toyota when the drug Avandia kills 300 people a month?
Do you think it’s so government motors GM can sell some cars and that the pols know that “big Pharma” will cut off their campaign contributions ? Shouldn’t the CEO of Glasco Smith Kline be in front of a committee or in jail for murder..what about the FDA director? they knew/know the drug is killing people!
No meds here Esther.I don’t do drugs.
A: Because Toyota is Japanese and the US prefers to get rid of foreign competition.
Q: Which law firm is handling avandia class action suits?
Which law firm is handling avandia class action suits?
Q: Is There A Class Action Suit In Effect For Avandia?
I would like to inquire is anyone knows if there is now in effect a class action suit for avandia ?
My mom would like to get in the suit if there is because we feel this is what caused my dad to die of a heart attack.
Any information you may have would help on this important issue!
A: Lawsuits are being investigated following the New England Journal of Medicine analysis which indicates users may face a 43% increase in the risk of heart attacks and a 64% increase in the risk of heart related death.
More information is at this website…
Q: I am a type 2 diabetic and am taking Avandia and Amaryl can they make you gain weight as a side effect?
Am i fighting a losing battle by taking my meds to get my blood sugar under control and eating right to help lose weight,but the side effects of these diabetes meds making me experience weight gain?
A: People taking Avandia alone gained about four to six pounds (on average) over a year, while people not taking Avandia lost about two pounds during the year. When Avandia was combined with insulin or certain other oral diabetes medications, the amount of weight gain increased up to about 12 pounds.
In these studies, people who were taking higher doses of Avandia (8 mg) gained more weight than people taking lower doses of Avandia (4 mg). Also, taking Avandia with metformin (Glucophage®) seemed to slightly decrease the amount of weight gained.
There are a number of possible side effects with Avandia® (rosiglitazone maleate). Weight gain does appear to be one of them. This data comes from clinical trials where Avandia was extensively studied and its side effects were documented.
One thing to keep in mind is that rapid weight gain (more than three to five pounds in a week) is a possible sign of congestive heart failure, another known problem with Avandia.
The “glitazone” diabetes drugs Actos and Avandia may double or triple the risk of broken bones after a year or two of use.
The finding comes from Swiss researchers who analyzed 12 years of data on U.K. diabetes patients. They compared the 1,020 patients who suffered some kind of fracture to 3,728 matched patients who did not break any bones.
Over the course of the study, most of the patients took several diabetes drugs. But those who refilled their Actos or Avandia prescriptions eight times or more — about 12 to 18 months of use — had nearly twice the fracture risk of other patients.
And those who refilled their Actos or Avandia prescriptions 15 times or more — two or more years of treatment — nearly tripled their risk of fracture, found Christophe R. Meier, PhD, head of pharmacoepidemiology research at University Hospital Basel, Switzerland, and colleagues.
Avandia is a killer drug. Best to discontinue and switch to metformin. Shame on your doctor for prescribing it for you.
Q: Is it right to take Diamicron,Glucophage and Avandia every day?
I am a diabetic man and my doctor prescribed me the following medication to be taken daily: Diamicron, Glucophage and Avandia.
A: Absolutely ONLY if your Doctor advises you to do so. And then if you do have some of the very bad side affects that can occur, stop immediately and confer with your Doctor again on the problems.
Q: Has anyone been prescribed Avandia to lower blood sugar and help them ovulate?
My doctor recently put me on Avandia to lower my blood sugar, hoping to help me ovulate. Has anyone else heard of this, or been prescribed this?? Any advice would help.. Thanks!
The doctor said I have type 2 diabetes… Have you heard of this? or have you been put on Avandia? Thanks for replying!!
ntn… do you think that avandia will adventually help me with a good diet and exercise?
A: Do you have diabetes? I have heard that if you have diabetes and it isn’t controlled well then you might have trouble conceiving.
Q: Anyone have weight gain on a combo of Avandia and Lyrica?
I want to know if this is a common thing or just my bad luck. I gained 40 lbs. in 6 months after starting Avandia. I have been on Lyrica for almost a year. I found some reference to this side effect in the company literature for one or the other med. Figured this one out the same day the big heart attack scare hit the news. I dropped Avandia w/ Dr’s agreement.
A: Lyrica can contribute to weight gain- I’ve never been on Avandia, but I know that Lyrica has common side effects of weight gain. Have you brought this up with your doctor…it may be a good idea.